Acyl bromides
Medchemexpress LLC (2e)-1-(3,4-dimethoxyphenyl)-5-fluoro-3-(4-fluorophenyl)-2-(2-fluorophenyl)pent-1-en-4-one bromide | 1390654-28-0 | >98.8% | 524.38 | 100 MG
KRN2 bromide is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6, without hindering high-salt-induced NFAT5 and its target gene expressions. KRN2 also dose-dependently inhibits NF-κB p65 binding to Nfat5 promoter 1 and directly blocks the interaction between NF-κB p65 and its DNA binding sequence in the upstream site of Nfat5 exon 1.
- Effectively suppresses AIA in which innate immune cells play a predominant role.
- Effectively suppresses CIA as well as AIA in mice.
- Decreases the production of pro-inflammatory cytokines and autoantibodies.
- Reduces macrophage infiltration.
Cayman Chemical N4-benzoyl-2'-Deoxycytidine, Purity: ≥98%, CAS: 4836-13-9, 10 g
A building block; has been used in the synthesis of nucleosides and nucleotides with anticancer activity, as well as oligonucleotides
Apexbio Technology LLC Mepenzolate Bromide 76-90-4 10mM (in 1mL DMSO)
Mepenzolate bromide (CAS 76-90-4) is a synthetic quaternary ammonium compound that functions as a muscarinic acetylcholine receptor antagonist By inhibiting parasympathetic neural transmission it reduces gastric secretion and gastrointestinal motility Mepenzolate bromide is generally supplied as a white to light cream powder with high solubility in methanol limited solubility in water and chloroform and minimal solubility in ether This compound is widely employed in research investigating modulation of cholinergic signaling gastrointestinal physiology and autonomic pharmacology and serves as a tool compound for studying antimuscarinic mechanisms in vitro and in vivo
Medchemexpress LLC N6-benzoyl-2'-deoxyadenosine monohydrate | 305808-19-9 | 98.0% | 373.36 | C17H19N5O5 | 25 G
N6-benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analog used in biochemical research and oligonucleotide synthesis. Supplied as a solid monohydrate, it is used in diagnostic and analytical workflows that require modified nucleosides.
- Nucleoside analog used in oligonucleotide synthesis and nucleoside research.
- Monohydrate solid form for easier handling and storage.
- High purity (98.0%) suitable for research applications.
- Chemical formula C17H19N5O5; molecular weight 373.36.
- Available in common laboratory pack sizes, including 25 G.
- Applicable in diagnostic and analytical workflows requiring DNA binding or modification.
AdipoGen 10-Octadecylacridine orange Br
Chemical. CAS 75168-16-0. Formula C35H56BrN3. MW 598.74. Synthetic. Fluorescent reagent with high selectivity. Potential sensitive dye PSD to monitor differences in cell potential as they occur during ion transport through the cell membrane.
AdipoGen Methyltrioctadecylammonium Br
Chemical. CAS 18262-86-7. Formula C55H114BrN. MW 869.42. Synthetic. Triple chain lipid. Long chain ionophore used in anion exchange for perchlorate-selective membranes. This is as sensing material with selectivity of chloride-selective polymeric membrane electrode. Organic surfactant. Used as alkylammonium cations for the design of layered chemical sensors.
Cayman Chemical N4-benzoyl-2'-Deoxycytidine, Purity: ≥98%, CAS: 4836-13-9, 5 g
A building block; has been used in the synthesis of nucleosides and nucleotides with anticancer activity, as well as oligonucleotides
AdipoGen Stain 7-I
Chemical. CAS 155862-95-6. Formula C27H22BrN3O6. MW 564.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance.
Cayman Chemical p-Benzoyl-L-phenylalanine, Purity: ≥95%, CAS: 104504-45-2, 500 mg
A photoreactive derivative of L-phenylalanine; can be incorporated into synthetic peptides and used as a photolabel to identify the residues involved in peptide-protein interactions; has been incorporated into GPCRs to identify potential ligand binding sites
Cayman Chemical p-Benzoyl-L-phenylalanine, Purity: ≥95%, CAS: 104504-45-2, 1 g
A photoreactive derivative of L-phenylalanine; can be incorporated into synthetic peptides and used as a photolabel to identify the residues involved in peptide-protein interactions; has been incorporated into GPCRs to identify potential ligand binding sites
Apexbio Technology LLC Tiotropium Bromide hydrate 139404-48-1 10mg
Tiotropium Bromide hydrate is a small-molecule antagonist targeting muscarinic acetylcholine receptors (mAChRs) It is designed to competitively inhibit mAChRs thereby modulating airway smooth muscle contraction and mediating bronchodilation Tiotropium Bromide hydrate exerts its biological activity primarily through competitive antagonism at mAChRs resulting in relaxation of airway smooth muscle Based on these pharmacological properties Tiotropium Bromide hydrate holds research potential in respiratory pharmacology particularly for investigating mechanistic pathways in chronic obstructive pulmonary disease (COPD) receptor-ligand interactions and pulmonary pharmacodynamics associated with airway obstruction
Apexbio Technology LLC Cetrimonium Bromide (CTAB) 57-09-0 10mM (in 1mL DMSO)
Cetrimonium Bromide (CTAB) (CAS 57-09-0) is a cationic surfactant that exerts its biological activity primarily through disruption of microbial membrane integrity via electrostatic interactions with negatively charged membrane components CTAB demonstrates antimicrobial activity by inhibiting microbial growth in in vitro assays Commonly employed in molecular biology protocols CTAB facilitates nucleic acid extraction through cellular lysis precipitation and purification particularly in plant genomic DNA isolation Additionally it is useful for antiseptic formulation studies nanoparticle synthesis and pharmaceutical research including drug delivery system development and stability studies
Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-25mg
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2
Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-1g
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2